| | 中外野手 | Sent to Minors (The St. Louis Cardinals optioned OF Victor Scott to the minors.) |
| | 一壘手 | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Pedro Pagés from the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned RHP Andre Pallante to the minors.) |
| | 投手 | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Nick Robertson from the minors.) |
| | 左外野手 | Activated (The St. Louis Cardinals activated OF Lars Nootbaar from the 10-day injured list.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals optioned C Pedro Pagés to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned LHP John King to the minors.) |
| | 投手 | Activated (The St. Louis Cardinals activated RHP Sonny Gray from the 15-day injured list.) |
| | 一壘手 | Recalled From Minors Rehab (The St. Louis Cardinals recalled C Pedro Pagés from the minors.) |
| | 指定打擊 | Placed on 10-Day IL (The St. Louis Cardinals placed DH Matt Carpenter on the 10-day injured list with an oblique strain.) |
| | 左外野手 | Sent to Minors (The St. Louis Cardinals sent LF Lars Nootbar to the minors on a rehab assignment.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals sent INF Jared Young outright to the minors.) |
| | 投手 | Placed on 15-Day IL (The St. Louis Cardinals placed RP Riley O'Brien on the 15-Day Injury List with a flexor strain in his right forearm.) |
| | 投手 | Recalled From Minors Rehab (The St. Louis Cardinals recalled RP John King from the minors.) |
| | 投手 | Placed on 15-Day IL (The St. Louis Cardinals placed LHP Drew Rom on the 15-day injured list.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals optioned C Pedro Pagés to the minors.) |
| | 二壘手 | Sent to Minors (The St. Louis Cardinals optioned INF José Fermín to the minors.) |
| | 游擊手 | Placed on 10-Day IL (The St. Louis Cardinals placed INF Tommy Edman on the 10-day injured list.) |
| | 投手 | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Keynan Middleton on the 15-day injured list.) |
| | 左外野手 | Placed on 10-Day IL (The St. Louis Cardinals placed OF Lars Nootbaar on the 10-day injured list.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned LHP John King to the minors.) |
| | 投手 | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Sonny Gray on the 15-day injured list.) |
| | 中外野手 | Placed on 10-Day IL (The St. Louis Cardinals placed OF Dylan Carlson on the 10-day injured list.) |
| | 一壘手 | Designated for Assignment (The St. Louis Cardinals designated INF Jared Young for assignment.) |
| | 中外野手 | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of OF Victor Scott from the minors.) |
| | 游擊手 | Sent to Minors (The St. Louis Cardinals sent INF César Prieto to the minors.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals optioned INF Luken Baker to the minors.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals optioned INF Jared Young to the minors.) |
| | 中外野手 | Sent to Minors (The St. Louis Cardinals sent OF Victor Scott to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned RHP Nick Robertson to the minors.) |
| | 一壘手 | Sent to Minors (The St. Louis Cardinals optioned INF Alfonso Rivas to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned RHP Ryan Loutos to minor league camp.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned RHP Gordon Graceffo to minor league camp.) |
| | 游擊手 | Sent to Minors (The St. Louis Cardinals assigned INF Jeremy Rivas to minor league camp.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned RHP Sem Robberse to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned LHP Connor Thomas to minor league camp.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned RHP Michael McGreevy to minor league camp.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned RHP Tekoah Roby to minor league camp.) |
| | 游擊手 | Sent to Minors (The St. Louis Cardinals assigned INF Arquímedes Gamboa to minor league camp.) |
| | 捕手 | Sent to Minors (The St. Louis Cardinals assigned C Aaron Antonini to minor league camp.) |
| | 捕手 | Sent to Minors (The St. Louis Cardinals assigned C Jimmy Crooks to minor league camp.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned RHP Adam Kloffenstein to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals assigned LHP Cooper Hjerpe to minor league camp.) |
| | 左外野手 | Sent to Minors (The St. Louis Cardinals sent OF Moisés Gómez to the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals sent LHP Packy Naughton to the minors.) |
| | 二壘手 | Designated for Assignment (The St. Louis Cardinals designated INF Buddy Kennedy for assignment.) |
| | 游擊手 | Signed (The St. Louis Cardinals signed INF Brandon Crawford.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Jacob Bosiokovic to a minor league contract.) |
| | 投手 | Traded (The St. Louis Cardinals traded RHP Guillermo Zuñiga to the Los Angeles Angels.) 至 |
| | 左外野手 | Non-roster Invitee (The St. Louis Cardinals invited OF Moisés Gómez to spring training.) |
| | 投手 | Designated for Assignment (The St. Louis Cardinals designated RHP Guillermo Zuñiga for assignment.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Keynan Middleton.) |
| | 左外野手 | Designated for Assignment (The St. Louis Cardinals designated OF Moisés Gómez for assignment.) |
| | 一壘手 | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed INF Alfonso Rivas from the Los Angeles Angels.) |
| | 投手 | Non-roster Invitee (The St. Louis Cardinals invited non-roster RHP Josh James to spring training.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Josh James to a minor league contract.) |
| | 投手 | Signed (The St. Louis Cardinals signed LHP Nick Raquet to a minor league contract.) |
| | 捕手 | Signed (The St. Louis Cardinals signed C Jonathan Morales to a minor league contract.) |
| | 投手 | Signed (The St. Louis Cardinals signed LHP Nick Raquet to a minor league contract.) |
| | 捕手 | Signed (The St. Louis Cardinals signed C Jonathan Morales to a minor league contract.) |
| | 指定打擊 | Signed (The St. Louis Cardinals signed DH Matt Carpenter.) |
| | 投手 | Declared Free Agency (RHP James Naile elected free agency.) |
| | 投手 | Traded (The Tampa Bay Rays traded RHP Andrew Kittredge to the St. Louis Cardinals.) 從 |
| | 右外野手 | Traded (The St. Louis Cardinals traded INF Richie Palacios to the Tampa Bay Rays.) 至 |
| | 捕手 | Signed (The St. Louis Cardinals signed C Gavin Collins to a minor league contract.) |
| | 投手 | Traded (The Boston Red Sox traded RHP Victor Santos to the St. Louis Cardinals.) 從 |
| | 右外野手 | Traded (The St. Louis Cardinals traded OF Tyler O'Neill to the Boston Red Sox.) 至 |
| | 投手 | Traded (The Boston Red Sox traded RHP Nick Robertson to the St. Louis Cardinals.) 從 |
| | 投手 | Drafted Via Rule 5 (The St. Louis Cardinals selected RHP Benito Garcia in the Rule 5 Draft.) |
| | 三壘手 | Drafted Via Rule 5 (The St. Louis Cardinals selected INF Johnfrank Salazar in the Rule 5 Draft.) |
| | 游擊手 | Drafted Via Rule 5 (The St. Louis Cardinals selected INF Miguel Villarroel in the Rule 5 Draft.) |
| | 投手 | Drafted Via Rule 5 (The St. Louis Cardinals selected RHP Ryan Fernandez in the Rule 5 Draft.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Sonny Gray.) |
| | 投手 | Non-roster Invitee (The St. Louis Cardinals signed RHP Wilking Rodríguez to a minor league contract with an invitation to spring training.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Kyle Gibson.) |
| | 投手 | Signed (The St. Louis Cardinals signed RHP Lance Lynn.) |
| | 投手 | Released (The St. Louis Cardinals released RHP Dakota Hudson.) |
| | 投手 | Released (The St. Louis Cardinals released RHP Jake Woodford.) |
| | 左外野手 | Released (The St. Louis Cardinals released OF Juan Yepez.) |
| | 捕手 | Released (The St. Louis Cardinals released C Andrew Knizner.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals sent LHP Connor Thomas outright to the minors.) |
| | 投手 | Declared Free Agency (RHP Wilking Rodríguez declared free agency.) |
| | 投手 | Designated for Assignment (The St. Louis Cardinals designated LHP Connor Thomas for assignment.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals sent LHP Packy Naughton outright to the minors.) |
| | 投手 | Activated (The St. Louis Cardinals selected the contract of RHP Sem Robberse from the minors.) |
| | 一壘手 | Activated (The St. Louis Cardinals selected the contract of C Pedro Pagés from the minors.) |
| | 投手 | Activated (The St. Louis Cardinals selected the contract of RHP Adam Kloffenstein from the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals sent RHP Wilking Rodríguez outright to the minors.) |
| | 投手 | Declared Free Agency (RHP Jose Martinez declared free agency.) |
| | 二壘手 | Declared Free Agency (INF Irving Lopez declared free agency.) |
| | 投手 | Traded (The Seattle Mariners traded RHP Riley O'Brien to the St. Louis Cardinals.) 從 |
| | 一壘手 | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed INF Jared Young off waivers from the Chicago Cubs.) |
| | 投手 | Activated (The St. Louis Cardinals activated LHP Steven Matz.) |
| | 投手 | Activated (The St. Louis Cardinals activated RHP Jake Woodford.) |
| | 投手 | Activated (The St. Louis Cardinals activated RHP Giovanny Gallegos.) |
| | 投手 | Activated (The St. Louis Cardinals activated RHP Wilking Rodríguez from the 60-day injured list.) |
| | 左外野手 | Activated (The St. Louis Cardinals activated INF Brendan Donovan from the 60-day injured list.) |
| | 三壘手 | Activated (The St. Louis Cardinals activated INF Nolan Arenado.) |
| | 投手 | Activated (The St. Louis Cardinals activated LHP Packy Naughton from the 60-day injured list.) |
| | 左外野手 | Activated (The St. Louis Cardinals activated OF Moisés Gómez.) |
| | 投手 | Activated (The St. Louis Cardinals activated RHP Guillermo Zuñiga from the 60-day injured list.) |
| | 捕手 | Activated (The St. Louis Cardinals activated C Willson Contreras.) |
| | 中外野手 | Activated (The St. Louis Cardinals activated OF Dylan Carlson from the 60-day injured list.) |
| | 二壘手 | Activated (The St. Louis Cardinals activated INF Nolan Gorman.) |
| | 二壘手 | Activated (The St. Louis Cardinals activated INF Buddy Kennedy.) |
| | 右外野手 | Activated (The St. Louis Cardinals activated OF Tyler O'Neill.) |
| | 右外野手 | Activated (The St. Louis Cardinals activated OF Alec Burleson.) |
| | 投手 | Activated (The St. Louis Cardinals activated LHP JoJo Romero.) |
| | 投手 | Activated (The St. Louis Cardinals activated LHP Connor Thomas.) |
| | 投手 | Declared Free Agency (St. Louis Cardinals RHP Drew VerHagen declared free agency.) |
| | 三壘手 | Declared Free Agency (INF Juniel Querecuto declared free agency.) |
| | 投手 | Declared Free Agency (RHP Jacob Barnes declared free agency.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals sent RHP Kyle Leahy outright to the minors.) |
| | 三壘手 | Sent to Minors (The St. Louis Cardinals sent INF Juniel Querecuto outright to the minors.) |
| | 投手 | Declared Free Agency (LHP Andrew Suárez declared free agency.) |
| | 二壘手 | Sent to Minors (The St. Louis Cardinals sent INF Irving Lopez outright to the minors.) |
| | 投手 | Declared Free Agency (RHP Casey Lawrence declared free agency.) |
| | 投手 | Retired (RHP Adam Wainwright retired from Major League Baseball.) |
| | 二壘手 | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed INF Buddy Kennedy off waivers from the Oakland Athletics.) |
| | 投手 | Released (The St. Louis Cardinals released RHP Cory Thompson.) |
| | 游擊手 | Released (The St. Louis Cardinals released INF Kramer Robertson.) |
| | 游擊手 | Released (The St. Louis Cardinals released INF Errol Robinson.) |
| | 中外野手 | Released (The St. Louis Cardinals released OF Chase Pinder.) |
| | 捕手 | Released (The St. Louis Cardinals released C José Alvarez.) |
| | 捕手 | Declared Free Agency (C Tres Barrera declared free agency.) |
| | 二壘手 | Declared Free Agency (INF Taylor Motter elected free agency.) |
| | 三壘手 | Released (The St. Louis Cardinals released INF Francisco Hernandez.) |
| | 中外野手 | Released (The St. Louis Cardinals released OF Tyler Reichenborn.) |
| | 一壘手 | Released (The St. Louis Cardinals released INF Thomas Francisco.) |
| | 投手 | Released (The St. Louis Cardinals released RHP Matt Hickey.) |
| | 投手 | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP James Naile from the minors.) |
| | 投手 | Sent to Minors (The St. Louis Cardinals optioned RHP Jake Woodford to the minors.) |
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